Salmeterol It is the first long acting selective β2 agonist with a slow onset of action; used by inhalation on a twice daily schedule for maintenance therapy and for occurring asthma, but not for acute symptoms. Salmeterol reduces breathlessness by preventing expiratory closure of peripheral airways and abolishing the reversible component of airway obstruction. Fluticasone is an Inhaled steroid it suppresses bronchial inflammation, increase peak expiratory flow rate, reduce need for rescue β2-agonist inhalations and prevent episodes of acute asthma.
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