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Ramipril The distinctive feature of this long-acting ACE(angiotensin-converting enzyme) inhibitor is its extensive tissue distribution. Greater inhibition of local RAS(Renin-angiotensin system) has been claimed.it is used in the treatment of hypertension, CHF, Myocardial Infection, etc.Hydrochlorothiazide is thiazide and related diuretics used to treat hypertesnion and oedemas and renal calculi.