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Budesonide are glucocorticoids with high topical and low systemic activity (due to poor absorption and/ or marked first pass metabolism). Inhaled steroids suppress bronchial inflammation, increase peak expiratory flow rate, reduce need for rescue β2-agonist inhalations and prevent episodes of acute asthma and also used to treat Nasal irritation, sneezing, crusting, itching of throat and dryness may occur, especially in the beginning. Contraindicated in presence of infection or nasal ulcers.